Dandy-Walker syndrome presenting as opisthotonus: proposed pathophysiology.


Journal Article

A patient with radiographically confirmed Dandy-Walker syndrome who presented with opisthotonus, a rarely reported clinical manifestation, is reported. From four separate pharmacologic trials (baclofen, diazepam, levodopa/carbidopa, and trihexyphenidyl), combination baclofen and diazepam therapy was determined to be most efficacious. Opisthotonus and extensor posturing remain only rudimentarily understood. We review the subject and propose a specific mechanism relating our patient's anatomic and physiologic conditions.

Full Text

Cited Authors

  • Ondo, WG; Delong, GR

Published Date

  • February 1996

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 165 - 168

PubMed ID

  • 8703233

Pubmed Central ID

  • 8703233

International Standard Serial Number (ISSN)

  • 0887-8994

Digital Object Identifier (DOI)

  • 10.1016/0887-8994(96)00014-8


  • eng

Conference Location

  • United States