Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma).

Journal Article (Journal Article)

The epithelioid variant of malignant peripheral nerve sheath tumor (MPNST), also known as malignant epithelioid schwannoma, is a relatively rare and recently characterized clinicopathologic entity. The epithelioid variant of MPNST shares many clinical features with conventional MPNST but is characterized by different histologic and cytologic features. These include a distinctive nesting pattern and an abundance of cytoplasm not seen in histology of conventional nerve sheath tumors. Cytologically, the epitheliod variant shows a propensity to cellular discohesiveness and a plasmacytoid or epitheliod appearance that is in contradistinction to the spindled appearance of the usual MPNST. Herein, we report our experience with fine-needle aspiration (FNA) of two epithelioid malignant schwannomas and discuss the FNA cytologic differential diagnosis.

Full Text

Duke Authors

Cited Authors

  • Dodd, LG; Scully, S; Layfield, LJ

Published Date

  • September 1997

Published In

Volume / Issue

  • 17 / 3

Start / End Page

  • 200 - 204

PubMed ID

  • 9285192

International Standard Serial Number (ISSN)

  • 8755-1039

Digital Object Identifier (DOI)

  • 10.1002/(sici)1097-0339(199709)17:3<200::aid-dc6>;2-i


  • eng

Conference Location

  • United States