Fine-needle aspiration cytology of silicone granulomas in the augmented breast.

Journal Article (Journal Article)

We studied 12 aspirates from 10 patients who underwent diagnostic fine-needle aspiration cytology (FNAC) of an augmented or reconstructed breast. Six patients were augmented with silicone gel-filled implants and four patients had silicone liquid injections. FNAC indications included a painful or suspicious mass. Excisional biopsy was performed in six cases after FNAC. The findings of eight cases included modestly cellular smears composed of loosely cohesive histiocytes containing vacuoles of various sizes. Multinucleated foreign body giant cells, fragments of dense, amorphous fibrous tissue, and fibroblast nuclei stripped of cytoplasm were also present. Two patients showed a mixture of inflammatory cells characteristic of intramammary lymph nodes or lymphoid aggregates. We conclude that silicone granulomas of the breast show a characteristic set of findings on FNAC which enable a cytopathologist to render a specific diagnosis given an appropriate history of breast augmentation.

Full Text

Duke Authors

Cited Authors

  • Dodd, LG; Sneige, N; Reece, GP; Fornage, B

Published Date

  • October 1993

Published In

Volume / Issue

  • 9 / 5

Start / End Page

  • 498 - 502

PubMed ID

  • 8287755

International Standard Serial Number (ISSN)

  • 8755-1039

Digital Object Identifier (DOI)

  • 10.1002/dc.2840090505


  • eng

Conference Location

  • United States