Diagnosis of anaplastic large-cell lymphoma, including multifocal osseous KI-1 lymphoma, by fine-needle aspiration biopsy.

Journal Article (Journal Article)

We present the fine-needle aspiration (FNA) findings of 4 cases of anaplastic (Ki-1) large-cell lymphoma (ALCL). A primary diagnosis of ALCL was made on FNA material in 2 cases, of which one was a multifocal osseous Ki-1 lymphoma. In the other 2 patients who had a known history of ALCL, FNA was used to detect recurrent disease. In all cases, large discohesive pleomorphic cells in the absence of lymphoglandular bodies in the background raised the possibility of a nonhematopoietic neoplasm. Immunochemical staining for CD30 was positive in all cases. The cytomorphologic and immunochemical features are discussed, along with the differential diagnosis of Ki-1 lymphoma. Diagn. Cytopathol. 1999;21:174-179.

Full Text

Duke Authors

Cited Authors

  • Liu, K; Dodd, LG; Osborne, BM; Martinez, S; Olatdioye, BA; Madden, JF

Published Date

  • September 1999

Published In

Volume / Issue

  • 21 / 3

Start / End Page

  • 174 - 179

PubMed ID

  • 10450102

International Standard Serial Number (ISSN)

  • 8755-1039

Digital Object Identifier (DOI)

  • 10.1002/(sici)1097-0339(199909)21:3<174::aid-dc6>3.0.co;2-q


  • eng

Conference Location

  • United States