Cytomorphologic features of sebaceous carcinoma on fine needle aspiration.

Journal Article (Journal Article)

OBJECTIVE: To describe three cases of sebaceous carcinoma metastatic to regional lymph nodes diagnosed by fine needle aspiration (FNA). STUDY DESIGN: FNA was performed using standard techniques. A portion of each specimen was stained with Diff-Quick (Dade, Miami, Florida, U.S.A.); another portion was fixed in 95% ethanol and stained with a modified Papanicolaou stain or fixed in formalin and stained with hematoxylin and eosin. RESULTS: All carcinomas were moderately cellular, with primarily irregular cell clusters. The cytoplasm was finely reticular and contained variable numbers of small vaculoes. Nuclei were centrally located and pleomorphic and contained coarse chromatin. Variably sized but often large nucleoli were seen. Mitotic figures were easily identified. CONCLUSION: Sebaceous carcinoma is a rare but cytologically distinct neoplasm. It frequently metastasizes to regional lymph nodes and may then appear as a mass amenable to FNA. Aspiration cytologists, particularly those who aspirate head and neck lesions, should be familiar with the distinct features of this neoplasm.

Full Text

Duke Authors

Cited Authors

  • Stern, RC; Liu, K; Dodd, LG

Published Date

  • September 2000

Published In

Volume / Issue

  • 44 / 5

Start / End Page

  • 760 - 764

PubMed ID

  • 11015976

International Standard Serial Number (ISSN)

  • 0001-5547

Digital Object Identifier (DOI)

  • 10.1159/000328558


  • eng

Conference Location

  • Switzerland