Progressive hepatic injury in prolonged parenteral alimentation.

Journal Article (Journal Article)

A morphologic sequence of progressive hepatic injury is demonstrated in an immature infant who received TPN for 148 days. Because immature infants are susceptible to multiple pathophysiologic insults, it is presently impossible to isolate a single etiologic agent responsible for hepatic dysfunction. It is important for physicians caring for immature infants to establish through biochemical and morphologic monitoring that appropriate duration for TPN which is not likely to lead to irreversible hepatic injury.

Full Text

Duke Authors

Cited Authors

  • Woodard, BH; Shifman, M; Bradford, WD

Published Date

  • December 1, 1980

Published In

Volume / Issue

  • 73 / 12

Start / End Page

  • 1659 - 1660

PubMed ID

  • 6777877

International Standard Serial Number (ISSN)

  • 0038-4348

Digital Object Identifier (DOI)

  • 10.1097/00007611-198012000-00040


  • eng

Conference Location

  • United States