Pathogen-induced systemic DNA rearrangement in plants.
Infection of tobacco plants with tobacco mosaic virus and oilseed rape mosaic virus was shown to induce a threefold increase in homologous DNA recombination in non-infected tissues. Grafting experiments by Igor Kovalchuk et al. demonstrated that this increase was mediated by a systemic recombination signal that traveled ahead of the virus. A similar increase in DNA recombination was also observed in the progeny of the infected plants, indicating that pathogen-induced recombination can lead to heritable adaptations to environmental stresses.
Volume / Issue
Start / End Page
Pubmed Central ID
Electronic International Standard Serial Number (EISSN)
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)