Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance.
Publication
, Journal Article
Cao, H; Li, X; Dong, X
Published in: Proceedings of the National Academy of Sciences of the United States of America
May 1998
The recently cloned NPR1 gene of Arabidopsis thaliana is a key regulator of acquired resistance responses. Upon induction, NPR1 expression is elevated and the NPR1 protein is activated, in turn inducing expression of a battery of downstream pathogenesis-related genes. In this study, we found that NPR1 confers resistance to the pathogens Pseudomonas syringae and Peronospora parasitica in a dosage-dependent fashion. Overexpression of NPR1 leads to enhanced resistance with no obvious detrimental effect on the plants. Thus, for the first time, a single gene is shown to be a workable target for genetic engineering of nonspecific resistance in plants.
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Published In
Proceedings of the National Academy of Sciences of the United States of America
DOI
EISSN
1091-6490
ISSN
0027-8424
Publication Date
May 1998
Volume
95
Issue
11
Start / End Page
6531 / 6536
Citation
APA
Chicago
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NLM
Cao, H., Li, X., & Dong, X. (1998). Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proceedings of the National Academy of Sciences of the United States of America, 95(11), 6531–6536. https://doi.org/10.1073/pnas.95.11.6531
Cao, H., X. Li, and X. Dong. “Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance.” Proceedings of the National Academy of Sciences of the United States of America 95, no. 11 (May 1998): 6531–36. https://doi.org/10.1073/pnas.95.11.6531.
Cao H, Li X, Dong X. Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proceedings of the National Academy of Sciences of the United States of America. 1998 May;95(11):6531–6.
Cao, H., et al. “Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance.” Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 11, May 1998, pp. 6531–36. Epmc, doi:10.1073/pnas.95.11.6531.
Cao H, Li X, Dong X. Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proceedings of the National Academy of Sciences of the United States of America. 1998 May;95(11):6531–6536.
Published In
Proceedings of the National Academy of Sciences of the United States of America
DOI
EISSN
1091-6490
ISSN
0027-8424
Publication Date
May 1998
Volume
95
Issue
11
Start / End Page
6531 / 6536