Pleural space infections: microbiology and antimicrobial therapy.


Journal Article (Review)

Although most recognized pleural space infections are caused by Staphylococcus aureus, Streptococcus pneumoniae, enteric gram-negative bacilli, or anaerobic bacteria, the spectrum of possible pathogens is broad and includes fungi and even protozoa, reflecting the mixed origins of these infections. When pleural space infection is suspected, a diagnostic thoracocentesis is indicated. An immediate gram-stained smear of directly aspirated pleural fluid often can guide the physician's initial treatment. After recovery of the pathogens, optimal antibiotic therapy should be based on standardized susceptibility testing and consensus guidelines. Antibiotic therapy alone may be curative, but adequate drainage must also be achieved in most cases.

Full Text

Duke Authors

Cited Authors

  • Everts, RJ; Reller, LB

Published Date

  • March 1999

Published In

Volume / Issue

  • 14 / 1

Start / End Page

  • 18 - 30

PubMed ID

  • 10197394

Pubmed Central ID

  • 10197394

International Standard Serial Number (ISSN)

  • 0882-0546


  • eng

Conference Location

  • United States