Interpretive criteria and quality control parameters for determining bacterial susceptibility to fosfomycin tromethamine.

Published

Journal Article

Studies with fosfomycin tromethamine disks containing 200 micrograms of fosfomycin and 50 micrograms of glucose-6-phosphate confirmed the following zone diameter criteria for the NCCLS method: < or = 12 mm for resistant (MIC > or = 256 micrograms/ml), 13-15 mm for intermediate (MIC 128 micrograms/ml) and > or = 16 mm for susceptible (MIC < or = 64 micrograms/ml). Additional studies defined acceptable MIC and zone diameter ranges for the following quality control strains: Escherichia coli ATCC 25922, MIC 0.5 to 4.0 micrograms/ml, zone diameter 23 to 29 mm; Staphylococcus aureus ATCC 25923, zone diameter 26 to 32 mm; Pseudomonas aeruginosa ATCC 27813, MIC 2.0 to 8.0 micrograms/ml; and Enterococcus faecalis, ATCC 29212, MIC 16 to 64 micrograms/ml.

Full Text

Duke Authors

Cited Authors

  • Barry, AL; Pfaller, MA; Fuchs, PC; Tenover, FC; Reller, LB; Allen, SD; Hardy, DJ; Gerlach, EH

Published Date

  • May 1993

Published In

Volume / Issue

  • 12 / 5

Start / End Page

  • 352 - 356

PubMed ID

  • 8354302

Pubmed Central ID

  • 8354302

International Standard Serial Number (ISSN)

  • 0934-9723

Language

  • eng

Conference Location

  • Germany