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Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin.

Publication ,  Journal Article
Darouiche, RO; Fowler, VG; Adal, K; Kielhofner, M; Mansouri, D; Reller, LB
Published in: Antimicrob Agents Chemother
February 2002

Prosthetic heart valve sewing cuffs coated with minocycline and rifampin exhibited in vitro zones of inhibition against all 52 tested clinical isolates responsible for prosthetic valve endocarditis. An in vitro elution study of these coated sewing cuffs demonstrated residual zones of inhibition against Staphylococcus epidermidis for at least 4 weeks.

Duke Scholars

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

February 2002

Volume

46

Issue

2

Start / End Page

543 / 545

Location

United States

Related Subject Headings

  • Staphylococcus epidermidis
  • Rifampin
  • Prosthesis-Related Infections
  • Minocycline
  • Microbiology
  • Microbial Sensitivity Tests
  • Humans
  • Heart Valve Prosthesis
  • Drug Therapy, Combination
  • Bacillus
 

Citation

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Darouiche, R. O., Fowler, V. G., Adal, K., Kielhofner, M., Mansouri, D., & Reller, L. B. (2002). Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin. Antimicrob Agents Chemother, 46(2), 543–545. https://doi.org/10.1128/AAC.46.2.543-545.2002
Darouiche, Rabih O., Vance G. Fowler, Karim Adal, Marcia Kielhofner, David Mansouri, and L Barth Reller. “Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin.Antimicrob Agents Chemother 46, no. 2 (February 2002): 543–45. https://doi.org/10.1128/AAC.46.2.543-545.2002.
Darouiche RO, Fowler VG, Adal K, Kielhofner M, Mansouri D, Reller LB. Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin. Antimicrob Agents Chemother. 2002 Feb;46(2):543–5.
Darouiche, Rabih O., et al. “Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin.Antimicrob Agents Chemother, vol. 46, no. 2, Feb. 2002, pp. 543–45. Pubmed, doi:10.1128/AAC.46.2.543-545.2002.
Darouiche RO, Fowler VG, Adal K, Kielhofner M, Mansouri D, Reller LB. Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin. Antimicrob Agents Chemother. 2002 Feb;46(2):543–545.

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

February 2002

Volume

46

Issue

2

Start / End Page

543 / 545

Location

United States

Related Subject Headings

  • Staphylococcus epidermidis
  • Rifampin
  • Prosthesis-Related Infections
  • Minocycline
  • Microbiology
  • Microbial Sensitivity Tests
  • Humans
  • Heart Valve Prosthesis
  • Drug Therapy, Combination
  • Bacillus