Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin.


Journal Article

Prosthetic heart valve sewing cuffs coated with minocycline and rifampin exhibited in vitro zones of inhibition against all 52 tested clinical isolates responsible for prosthetic valve endocarditis. An in vitro elution study of these coated sewing cuffs demonstrated residual zones of inhibition against Staphylococcus epidermidis for at least 4 weeks.

Full Text

Duke Authors

Cited Authors

  • Darouiche, RO; Fowler, VG; Adal, K; Kielhofner, M; Mansouri, D; Reller, LB

Published Date

  • February 2002

Published In

Volume / Issue

  • 46 / 2

Start / End Page

  • 543 - 545

PubMed ID

  • 11796374

Pubmed Central ID

  • 11796374

Electronic International Standard Serial Number (EISSN)

  • 1098-6596

International Standard Serial Number (ISSN)

  • 0066-4804

Digital Object Identifier (DOI)

  • 10.1128/AAC.46.2.543-545.2002


  • eng