Will hyperthermia conquer the elusive hypoxic cell? Implications of heat effects on tumor and normal-tissue microcirculation.

Journal Article (Journal Article;Review)

In tumor radiobiology, the hypoxic cell has become especially important because of recent evidence of acute hypoxic regions within experimental tumors. The impact of hyperthermia on the development of acute hypoxia is discussed. Two experiments for studying hyperthermia and hypoxia in tumors are presented. Knowledge of the microenvironment of tumor cells will be necessary to understand and improve tumor control.

Full Text

Duke Authors

Cited Authors

  • Dewhirst, MW; Ozimek, EJ; Gross, J; Cetas, TC

Published Date

  • December 1, 1980

Published In

Volume / Issue

  • 137 / 3

Start / End Page

  • 811 - 817

PubMed ID

  • 7003650

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.137.3.7003650


  • eng

Conference Location

  • United States