HIV-1: is Nef a PAK animal?

Journal Article (Journal Article;Review)

HIV-1 Nef is clearly essential for efficient viral replication in vivo, but it has been difficult to determine why. Recent evidence that Nef specifically activates a PAK-dependent signalling cascade may be the first step in defining the mechanism of action of this enigmatic viral protein.

Full Text

Duke Authors

Cited Authors

  • Cullen, BR

Published Date

  • December 1, 1996

Published In

Volume / Issue

  • 6 / 12

Start / End Page

  • 1557 - 1559

PubMed ID

  • 8994811

International Standard Serial Number (ISSN)

  • 0960-9822

Digital Object Identifier (DOI)

  • 10.1016/s0960-9822(02)70770-7


  • eng

Conference Location

  • England