Evaluation of the growth hormone exercise test in normal and growth hormone-deficient children.

Journal Article (Academic Article)

A group of 168 short but otherwise normal children (group A) and 25 children deficient in growth hormone (GH) (group B) wwere studied with an exercise stimulation test to determine the expected error of this method. In group A, 125 (74.4%) had maximum GH responses greater than 15 ng/ml, 23 (13.7%) had responses between 10 and 15 ng/ml, and 20 (11.9%) had responses less than 10 ng/ml. The mean +/- SD values were 8.4 +/- 0.4 ng/ml at 0 time, 26.3 +/- 15.0 at 20 minutes, and 10.7 +/- 8.3 at 40 minutes. The mean maximum response was 27.7 +/- 14.3 ng/ml. In group B, 22 (88%) had maximum responses less than 10 ng/ml and 3 (12%) had responses between 10 and 15 ng/ml. Patients with maximum responses less than 10 ng/ml have a high probability of being GH-deficinet, whereas patients with responses between 10 and 15 ng/ml are less likely to be GH-deficient. No patients with responses greater than 15 ng/ml were GH-deficient.

Duke Authors

Cited Authors

  • Eisenstein, E; Plotnick, L; Lanes, R; Lee, PA; Migeon, CJ; Kowarski, AA

Published Date

  • October 1978

Published In

Volume / Issue

  • 62 / 4

Start / End Page

  • 526 - 528

International Standard Serial Number (ISSN)

  • 0031-4005

Conference Location

  • united states