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Solution structure of HI0257, a bacterial ribosome binding protein.

Publication ,  Journal Article
Parsons, L; Eisenstein, E; Orban, J
Published in: Biochemistry
September 2001

A novel bacterial ribosome binding protein, protein Y (also known as YfiA), was recently shown to reside at the 30S/50S subunit interface and to stabilize the ribosomal 70S complex against dissociation at low magnesium ion concentrations. We report here the three-dimensional NMR structure in solution of a homologue from Haemophilus influenzae, HI0257, that has 64% sequence identity to protein Y. The 107 residue protein has a beta-alpha-beta-beta-beta-alpha folding topology with two parallel alpha-helices packed against the same side of a four-stranded beta-sheet. The closest structural relatives are proteins with the double-stranded RNA-binding domain (dsRBD) motif although there is little (

Duke Scholars

Published In

Biochemistry

ISSN

0006-2960

Publication Date

September 2001

Volume

40

Issue

37

Start / End Page

10979 / 10986

Location

united states

Related Subject Headings

  • Biochemistry & Molecular Biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology
  • 0304 Medicinal and Biomolecular Chemistry
 

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Parsons, L., Eisenstein, E., & Orban, J. (2001). Solution structure of HI0257, a bacterial ribosome binding protein. Biochemistry, 40(37), 10979–10986.
Parsons, L., E. Eisenstein, and J. Orban. “Solution structure of HI0257, a bacterial ribosome binding protein.Biochemistry 40, no. 37 (September 2001): 10979–86.
Parsons L, Eisenstein E, Orban J. Solution structure of HI0257, a bacterial ribosome binding protein. Biochemistry. 2001 Sep;40(37):10979–86.
Parsons, L., et al. “Solution structure of HI0257, a bacterial ribosome binding protein.Biochemistry, vol. 40, no. 37, Sept. 2001, pp. 10979–86.
Parsons L, Eisenstein E, Orban J. Solution structure of HI0257, a bacterial ribosome binding protein. Biochemistry. 2001 Sep;40(37):10979–10986.
Journal cover image

Published In

Biochemistry

ISSN

0006-2960

Publication Date

September 2001

Volume

40

Issue

37

Start / End Page

10979 / 10986

Location

united states

Related Subject Headings

  • Biochemistry & Molecular Biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology
  • 0304 Medicinal and Biomolecular Chemistry