[Effects of N-acetylasparaginic acid during frontal lobectomy in the rat: antiamnestic action and effect on monoamine level].


Journal Article

Effects of N-acetyl-aspartic acid (NAA) on the behaviour models "open field", passive avoidance test and content of monoamines and their metabolites in the brain areas on the 9-th day after frontal decortication were studied. NAA (50 mg/kg), i.p., daily, 9 days) exerted antiamnestic effect in decorticated rats, evaluated in passive avoidance test. Corresponding changes in concentration of serotonin and 5-hydroxyindolacetic acid in the brain of decorticated rats were also seen.

Full Text

Duke Authors

Cited Authors

  • Grekhova, TV; Romanova, GA; Gaĭnetdinov, RR; Kudrin, VS; Raevskiĭ, KS

Published Date

  • February 1993

Published In

Volume / Issue

  • 115 / 2

Start / End Page

  • 159 - 161

PubMed ID

  • 8043794

Pubmed Central ID

  • 8043794

International Standard Serial Number (ISSN)

  • 0365-9615


  • rus

Conference Location

  • Russia (Federation)