Skip to main content
Journal cover image

The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT.

Publication ,  Journal Article
Krystal, AD; Weiner, RD; Coffey, CE
Published in: J Neuropsychiatry Clin Neurosci
1995

Relative stimulus intensity above seizure threshold has been shown to affect therapeutic outcome with unilateral ECT. The authors sought to explore whether a multivariate ictal EEG model would permit ongoing clinical assessment of this parameter. Twenty-five depressed subjects were randomized to either barely (T) or moderately (2.5T) suprathreshold ECT treatments. Seizures in 2.5T subjects had significantly greater ictal spectral amplitude and coherence, greater postictal suppression, and shorter latency until ictal slow-wave onset. A multivariate logistic regression ictal EEG model distinguished between stimulus intensity groups with 90% accuracy. Preliminary evidence suggests a relationship between several ictal EEG indices and therapeutic outcome. A multivariate ictal EEG algorithm holds promise as a tool for clinical determination of adequate stimulus intensity with unilateral ECT.

Duke Scholars

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1995

Volume

7

Issue

3

Start / End Page

295 / 303

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Regression Analysis
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Multivariate Analysis
  • Middle Aged
  • Mental Disorders
  • Male
  • Humans
  • Functional Laterality
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Krystal, A. D., Weiner, R. D., & Coffey, C. E. (1995). The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT. J Neuropsychiatry Clin Neurosci, 7(3), 295–303. https://doi.org/10.1176/jnp.7.3.295
Krystal, A. D., R. D. Weiner, and C. E. Coffey. “The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT.J Neuropsychiatry Clin Neurosci 7, no. 3 (1995): 295–303. https://doi.org/10.1176/jnp.7.3.295.
Krystal AD, Weiner RD, Coffey CE. The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT. J Neuropsychiatry Clin Neurosci. 1995;7(3):295–303.
Krystal, A. D., et al. “The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT.J Neuropsychiatry Clin Neurosci, vol. 7, no. 3, 1995, pp. 295–303. Pubmed, doi:10.1176/jnp.7.3.295.
Krystal AD, Weiner RD, Coffey CE. The ictal EEG as a marker of adequate stimulus intensity with unilateral ECT. J Neuropsychiatry Clin Neurosci. 1995;7(3):295–303.
Journal cover image

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1995

Volume

7

Issue

3

Start / End Page

295 / 303

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Regression Analysis
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Multivariate Analysis
  • Middle Aged
  • Mental Disorders
  • Male
  • Humans
  • Functional Laterality