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Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.

Publication ,  Journal Article
Woods, CW; McRill, C; Plikaytis, BD; Rosenstein, NE; Mosley, D; Boyd, D; England, B; Perkins, BA; Ampel, NM; Hajjeh, RA
Published in: J Infect Dis
April 2000

From 1 January 1995 through 31 June 1997, 153 cases of coccidioidomycosis in human immunodeficiency virus (HIV)-infected persons were identified in Arizona (incidence, 41/1000 persons living with AIDS). A case-control study was conducted to evaluate risk factors for coccidioidomycosis in HIV-infected persons. A case was defined as laboratory-confirmed, incident coccidioidomycosis in a person infected with HIV for > or =3 months, and each case patient had 3 control patients matched by county, age group, sex, HIV/AIDS status, and CD4 lymphocyte count. Multivariable analysis identified black race and a history of oropharyngeal or esophageal candidiasis to be associated with increased risk of coccidioidomycosis; protease inhibitor therapy was associated with a reduced risk. In persons with previous history of oropharyngeal or esophageal candidiasis, having received an azole drug was associated with a reduced risk (odds ratio, 0.4; 95% confidence interval, 0.2-0.9; P=.04). Physicians may need to consider azole chemoprophylaxis for HIV-infected persons who live in areas of endemicity, have CD4 cell counts <200/microL, are black, or have a history of thrush.

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Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

April 2000

Volume

181

Issue

4

Start / End Page

1428 / 1434

Location

United States

Related Subject Headings

  • Socioeconomic Factors
  • Risk Factors
  • Retrospective Studies
  • Oropharynx
  • Multivariate Analysis
  • Middle Aged
  • Microbiology
  • Male
  • Incidence
  • Humans
 

Citation

APA
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Woods, C. W., McRill, C., Plikaytis, B. D., Rosenstein, N. E., Mosley, D., Boyd, D., … Hajjeh, R. A. (2000). Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention. J Infect Dis, 181(4), 1428–1434. https://doi.org/10.1086/315401
Woods, C. W., C. McRill, B. D. Plikaytis, N. E. Rosenstein, D. Mosley, D. Boyd, B. England, B. A. Perkins, N. M. Ampel, and R. A. Hajjeh. “Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.J Infect Dis 181, no. 4 (April 2000): 1428–34. https://doi.org/10.1086/315401.
Woods CW, McRill C, Plikaytis BD, Rosenstein NE, Mosley D, Boyd D, et al. Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention. J Infect Dis. 2000 Apr;181(4):1428–34.
Woods, C. W., et al. “Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.J Infect Dis, vol. 181, no. 4, Apr. 2000, pp. 1428–34. Pubmed, doi:10.1086/315401.
Woods CW, McRill C, Plikaytis BD, Rosenstein NE, Mosley D, Boyd D, England B, Perkins BA, Ampel NM, Hajjeh RA. Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention. J Infect Dis. 2000 Apr;181(4):1428–1434.
Journal cover image

Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

April 2000

Volume

181

Issue

4

Start / End Page

1428 / 1434

Location

United States

Related Subject Headings

  • Socioeconomic Factors
  • Risk Factors
  • Retrospective Studies
  • Oropharynx
  • Multivariate Analysis
  • Middle Aged
  • Microbiology
  • Male
  • Incidence
  • Humans