An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98.

Journal Article (Journal Article)

In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV). Of the 171 persons enrolled in a cross-sectional study, 31(18%) were anti-RVFV immunoglobulin (Ig) M positive. An age-adjusted IgM antibody prevalence of 14% was estimated for the district. We estimate approximately 27,500 infections occurred in Garissa District, making this the largest recorded outbreak of RVFV in East Africa. In multivariable analysis, contact with sheep body fluids and sheltering livestock in one s home were significantly associated with infection. Direct contact with animals, particularly contact with sheep body fluids, was the most important modifiable risk factor for RVFV infection. Public education during epizootics may reduce human illness and deaths associated with future outbreaks.

Full Text

Duke Authors

Cited Authors

  • Woods, CW; Karpati, AM; Grein, T; McCarthy, N; Gaturuku, P; Muchiri, E; Dunster, L; Henderson, A; Khan, AS; Swanepoel, R; Bonmarin, I; Martin, L; Mann, P; Smoak, BL; Ryan, M; Ksiazek, TG; Arthur, RR; Ndikuyeze, A; Agata, NN; Peters, CJ; World Health Organization Hemorrhagic Fever Task Force,

Published Date

  • February 2002

Published In

Volume / Issue

  • 8 / 2

Start / End Page

  • 138 - 144

PubMed ID

  • 11897064

Pubmed Central ID

  • PMC2732454

International Standard Serial Number (ISSN)

  • 1080-6040

Digital Object Identifier (DOI)

  • 10.3201/eid0802.010023


  • eng

Conference Location

  • United States