Resolution of Budd-Chiari syndrome following bone marrow transplantation for paroxysmal nocturnal haemoglobinuria.
Journal Article (Journal Article)
Thrombosis of the hepatic veins (Budd-Chiari syndrome) is a life-threatening thrombotic complication which can occur in patients with paroxysmal nocturnal haemoglobinuria (PNH). Despite aggressive medical and surgical therapy, mortality from Budd-Chiari syndrome remains high. We report a boy with PNH who developed Budd-Chiari syndrome and underwent syngeneic bone marrow transplantation (BMT). Now, 3 years following BMT, he has had dramatic clinical and radiographic evidence of resolution of the thrombosis. We suggest that BMT for PNH can successfully correct life-threatening thrombosis in patients with PNH.
Full Text
Duke Authors
Cited Authors
- Graham, ML; Rosse, WF; Halperin, EC; Miller, CR; Ware, RE
Published Date
- March 1996
Published In
Volume / Issue
- 92 / 3
Start / End Page
- 707 - 710
PubMed ID
- 8616041
Pubmed Central ID
- 8616041
International Standard Serial Number (ISSN)
- 0007-1048
Digital Object Identifier (DOI)
- 10.1046/j.1365-2141.1996.365901.x
Language
- eng
Conference Location
- England