Synthetic and mechanistic studies of the cycloisomerization and cyclization/hydrosilylation of functionalized dienes catalyzed by cationic palladium(II) complexes.

Published

Journal Article (Review)

This Account describes the development and mechanistic study of the cycloisomerization and cyclization/hydrosilylation of functionalized dienes catalyzed by cationic palladium(II) complexes. These transformations are characterized by good functional group compatibility, high regio- and stereoselectivity, and low air- and moisture-sensitivity. Mechanistic studies of palladium phenanthroline-catalyzed diene cycloisomerization and cyclization/hydrosilylation established mechanisms involving C-C bond formation via intramolecular carbometalation of an alkyl olefin chelate complex, which was directly observed in the context of cyclization/hydrosilylation.

Full Text

Duke Authors

Cited Authors

  • Widenhoefer, RA

Published Date

  • October 2002

Published In

Volume / Issue

  • 35 / 10

Start / End Page

  • 905 - 913

PubMed ID

  • 12379143

Pubmed Central ID

  • 12379143

Electronic International Standard Serial Number (EISSN)

  • 1520-4898

International Standard Serial Number (ISSN)

  • 0001-4842

Digital Object Identifier (DOI)

  • 10.1021/ar010040n

Language

  • eng