Synthetic and mechanistic studies of the cycloisomerization and cyclization/hydrosilylation of functionalized dienes catalyzed by cationic palladium(II) complexes.
Journal Article (Review;Journal Article)
This Account describes the development and mechanistic study of the cycloisomerization and cyclization/hydrosilylation of functionalized dienes catalyzed by cationic palladium(II) complexes. These transformations are characterized by good functional group compatibility, high regio- and stereoselectivity, and low air- and moisture-sensitivity. Mechanistic studies of palladium phenanthroline-catalyzed diene cycloisomerization and cyclization/hydrosilylation established mechanisms involving C-C bond formation via intramolecular carbometalation of an alkyl olefin chelate complex, which was directly observed in the context of cyclization/hydrosilylation.
Full Text
Duke Authors
Cited Authors
- Widenhoefer, RA
Published Date
- October 2002
Published In
Volume / Issue
- 35 / 10
Start / End Page
- 905 - 913
PubMed ID
- 12379143
Electronic International Standard Serial Number (EISSN)
- 1520-4898
International Standard Serial Number (ISSN)
- 0001-4842
Digital Object Identifier (DOI)
- 10.1021/ar010040n
Language
- eng