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One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.

Publication ,  Journal Article
Li, P; Shaw, BR
Published in: Nucleosides, nucleotides & nucleic acids
May 2003

A one-pot synthesis of P-tyrosinyl(P-O)-5'-P-AZT boranophosphate 7 via a phosphoramidite method is described. The P-boranophosphate diastereomers were separated by RP-HPLC, and their structures were confirmed by NMR and MS.

Duke Scholars

Published In

Nucleosides, nucleotides & nucleic acids

DOI

EISSN

1532-2335

ISSN

1525-7770

Publication Date

May 2003

Volume

22

Issue

5-8

Start / End Page

699 / 701

Related Subject Headings

  • Zidovudine
  • Tyrosine
  • Prodrugs
  • Phosphates
  • Organic Chemistry
  • Indicators and Reagents
  • Boranes
  • Anti-HIV Agents
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Li, P., & Shaw, B. R. (2003). One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, Nucleotides & Nucleic Acids, 22(5–8), 699–701. https://doi.org/10.1081/ncn-120022613
Li, Ping, and Barbara Ramsay Shaw. “One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.Nucleosides, Nucleotides & Nucleic Acids 22, no. 5–8 (May 2003): 699–701. https://doi.org/10.1081/ncn-120022613.
Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, nucleotides & nucleic acids. 2003 May;22(5–8):699–701.
Li, Ping, and Barbara Ramsay Shaw. “One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.Nucleosides, Nucleotides & Nucleic Acids, vol. 22, no. 5–8, May 2003, pp. 699–701. Epmc, doi:10.1081/ncn-120022613.
Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, nucleotides & nucleic acids. 2003 May;22(5–8):699–701.

Published In

Nucleosides, nucleotides & nucleic acids

DOI

EISSN

1532-2335

ISSN

1525-7770

Publication Date

May 2003

Volume

22

Issue

5-8

Start / End Page

699 / 701

Related Subject Headings

  • Zidovudine
  • Tyrosine
  • Prodrugs
  • Phosphates
  • Organic Chemistry
  • Indicators and Reagents
  • Boranes
  • Anti-HIV Agents
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology