One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.
Publication
, Journal Article
Li, P; Shaw, BR
Published in: Nucleosides, nucleotides & nucleic acids
May 2003
A one-pot synthesis of P-tyrosinyl(P-O)-5'-P-AZT boranophosphate 7 via a phosphoramidite method is described. The P-boranophosphate diastereomers were separated by RP-HPLC, and their structures were confirmed by NMR and MS.
Duke Scholars
Published In
Nucleosides, nucleotides & nucleic acids
DOI
EISSN
1532-2335
ISSN
1525-7770
Publication Date
May 2003
Volume
22
Issue
5-8
Start / End Page
699 / 701
Related Subject Headings
- Zidovudine
- Tyrosine
- Prodrugs
- Phosphates
- Organic Chemistry
- Indicators and Reagents
- Boranes
- Anti-HIV Agents
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Li, P., & Shaw, B. R. (2003). One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, Nucleotides & Nucleic Acids, 22(5–8), 699–701. https://doi.org/10.1081/ncn-120022613
Li, Ping, and Barbara Ramsay Shaw. “One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.” Nucleosides, Nucleotides & Nucleic Acids 22, no. 5–8 (May 2003): 699–701. https://doi.org/10.1081/ncn-120022613.
Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, nucleotides & nucleic acids. 2003 May;22(5–8):699–701.
Li, Ping, and Barbara Ramsay Shaw. “One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.” Nucleosides, Nucleotides & Nucleic Acids, vol. 22, no. 5–8, May 2003, pp. 699–701. Epmc, doi:10.1081/ncn-120022613.
Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, nucleotides & nucleic acids. 2003 May;22(5–8):699–701.
Published In
Nucleosides, nucleotides & nucleic acids
DOI
EISSN
1532-2335
ISSN
1525-7770
Publication Date
May 2003
Volume
22
Issue
5-8
Start / End Page
699 / 701
Related Subject Headings
- Zidovudine
- Tyrosine
- Prodrugs
- Phosphates
- Organic Chemistry
- Indicators and Reagents
- Boranes
- Anti-HIV Agents
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology