Boranophosphate nucleic acids--a versatile DNA backbone.
Publication
, Journal Article
Rait, V; Sergueev, D; Summers, J; He, K; Huang, F; Krzyzanowska, B; Shaw, BR
Published in: Nucleosides & nucleotides
June 1999
Important chemical and biochemical properties of boranophosphate DNA and RNA oligonucleotides are reviewed. Stereoregular boranophosphate oligomers can be synthesized enzymatically and form stable duplexes with DNA. Fully boronated, non-stereoregular oligothymidylates, synthesized chemically, form hybrids with poly(A) that have lower melting points than oligothymidylate:poly(A), yet they nevertheless can support the RNase H mediated cleavage of RNA.
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Published In
Nucleosides & nucleotides
DOI
ISSN
0732-8311
Publication Date
June 1999
Volume
18
Issue
6-7
Start / End Page
1379 / 1380
Related Subject Headings
- Organophosphorus Compounds
- Organic Chemistry
- Nucleic Acids
- Nucleic Acid Conformation
- DNA
- Crystallography, X-Ray
- Boron Compounds
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
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Chicago
ICMJE
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Rait, V., Sergueev, D., Summers, J., He, K., Huang, F., Krzyzanowska, B., & Shaw, B. R. (1999). Boranophosphate nucleic acids--a versatile DNA backbone. Nucleosides & Nucleotides, 18(6–7), 1379–1380. https://doi.org/10.1080/07328319908044721
Rait, V., D. Sergueev, J. Summers, K. He, F. Huang, B. Krzyzanowska, and B. R. Shaw. “Boranophosphate nucleic acids--a versatile DNA backbone.” Nucleosides & Nucleotides 18, no. 6–7 (June 1999): 1379–80. https://doi.org/10.1080/07328319908044721.
Rait V, Sergueev D, Summers J, He K, Huang F, Krzyzanowska B, et al. Boranophosphate nucleic acids--a versatile DNA backbone. Nucleosides & nucleotides. 1999 Jun;18(6–7):1379–80.
Rait, V., et al. “Boranophosphate nucleic acids--a versatile DNA backbone.” Nucleosides & Nucleotides, vol. 18, no. 6–7, June 1999, pp. 1379–80. Epmc, doi:10.1080/07328319908044721.
Rait V, Sergueev D, Summers J, He K, Huang F, Krzyzanowska B, Shaw BR. Boranophosphate nucleic acids--a versatile DNA backbone. Nucleosides & nucleotides. 1999 Jun;18(6–7):1379–1380.
Published In
Nucleosides & nucleotides
DOI
ISSN
0732-8311
Publication Date
June 1999
Volume
18
Issue
6-7
Start / End Page
1379 / 1380
Related Subject Headings
- Organophosphorus Compounds
- Organic Chemistry
- Nucleic Acids
- Nucleic Acid Conformation
- DNA
- Crystallography, X-Ray
- Boron Compounds
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology