Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide.
Publication
, Journal Article
Li, P; Shaw, BR
Published in: Chemical communications (Cambridge, England)
December 2002
The first examples of a borane-containing doubly P-modified chiral cyclic nucleoside monophosphate (cNMP), e.g., thymidine and 5-fluoro-2'-deoxyuridine 3',5'-cyclic boranophosphorothioates, have been synthesized; these cNMP analogues with increased lipophilicity could be potential anticancer prodrugs and useful probes for mechanistic studies.
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Published In
Chemical communications (Cambridge, England)
DOI
EISSN
1364-548X
ISSN
1359-7345
Publication Date
December 2002
Issue
23
Start / End Page
2890 / 2891
Related Subject Headings
- Thymidine
- Thionucleotides
- Organic Chemistry
- Nucleotides, Cyclic
- Hydrophobic and Hydrophilic Interactions
- Drug Design
- Boranes
- Antineoplastic Agents
- 40 Engineering
- 34 Chemical sciences
Citation
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MLA
NLM
Li, P., & Shaw, B. R. (2002). Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide. Chemical Communications (Cambridge, England), (23), 2890–2891. https://doi.org/10.1039/b207350a
Li, Ping, and Barbara Ramsay Shaw. “Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide.” Chemical Communications (Cambridge, England), no. 23 (December 2002): 2890–91. https://doi.org/10.1039/b207350a.
Li P, Shaw BR. Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide. Chemical communications (Cambridge, England). 2002 Dec;(23):2890–1.
Li, Ping, and Barbara Ramsay Shaw. “Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide.” Chemical Communications (Cambridge, England), no. 23, Dec. 2002, pp. 2890–91. Epmc, doi:10.1039/b207350a.
Li P, Shaw BR. Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide. Chemical communications (Cambridge, England). 2002 Dec;(23):2890–2891.
Published In
Chemical communications (Cambridge, England)
DOI
EISSN
1364-548X
ISSN
1359-7345
Publication Date
December 2002
Issue
23
Start / End Page
2890 / 2891
Related Subject Headings
- Thymidine
- Thionucleotides
- Organic Chemistry
- Nucleotides, Cyclic
- Hydrophobic and Hydrophilic Interactions
- Drug Design
- Boranes
- Antineoplastic Agents
- 40 Engineering
- 34 Chemical sciences