Silane-promoted cycloisomerization of functionalized 1,6-dienes catalyzed by a cationic (π-allyl)palladium complex

Journal Article (Journal Article)

(matrix presented) A 1:1 mixture of the (π-allyl)palladium complex (η3-C3H5)Pd(Cl)PCy3 and NaB[3,5-C6H3(CF3)2]4 in the presence of HSiEt3 catalyzed the cycloisomerization of functionalized 1,6-dienes to form 1,2-disubstituted cyclopentenes in good yield with high selectivity (typically >94%). The protocol tolerated a range of functional groups and substitution at one of the allylic carbon atoms.

Full Text

Duke Authors

Cited Authors

  • Widenhoefer, RA; Perch, NS

Published Date

  • October 7, 1999

Published In

Volume / Issue

  • 1 / 7

Start / End Page

  • 1103 - 1105

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol9908981

Citation Source

  • Scopus