Polyzonimine: A novel terpenoid insect repellent produced by a milliped.


Journal Article

A nitrogen-containing terpene 6,6-dimethyl-2-azaspiro[4.4]non-1-ene (polyzonimine) was isolated from the defensive secretion of the milliped Polyzonium rosalbum. Polyzonimine, which is repellent to such natural enemies of the milliped as ants, acts as a topical irritant to insects (10-4 M induces scratching in cockroaches). Its structure was confirmed by a five-step synthesis starting from 2,2-dimethyl-7-oxabicyclo[4.1.0]heptane.

Full Text

Duke Authors

Cited Authors

  • Smolanoff, J; Kluge, AF; Meinwald, J; McPhail, A; Miller, RW; Hicks, K; Eisner, T

Published Date

  • May 1, 1975

Published In

Volume / Issue

  • 188 / 4189

Start / End Page

  • 734 - 736

PubMed ID

  • 1124395

Pubmed Central ID

  • 1124395

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.1124395


  • eng