Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines

Journal Article (Journal Article)

3-Phenyl- and 3-unsubstituted-2-alkenoyl-1-methylaziridines have been synthesized via Grignard reactions with the corresponding 2-cyanoaziridines. The 3-phenylated-2-alkenoylaziridines have been thermally transformed into ring-fused pyrrolidine compounds. The configurations and conformations of the aziridine and pyrrolidine compounds have been determined by 1H and 13C NMR spectroscopy and X-ray crystallography. © 1985, American Chemical Society. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Wenkert, D; Ferguson, SB; Porter, B; Qvarnstrom, A; McPhail, AT

Published Date

  • January 1, 1985

Published In

Volume / Issue

  • 50 / 21

Start / End Page

  • 4114 - 4119

Electronic International Standard Serial Number (EISSN)

  • 1520-6904

International Standard Serial Number (ISSN)

  • 0022-3263

Digital Object Identifier (DOI)

  • 10.1021/jo00221a029

Citation Source

  • Scopus