Enantioselectivity in camphor pinacolisation

Journal Article (Journal Article)

Total enantioselectivity has been observed in pinacol formation using Li/THF. (+) Camphor and (±) Camphor give the optically active and racemic form of a single pinacol whose stereochemistry has been established as endo:endo by X-ray analysis. An exo:endo pinacol is formed as the sole product if camphor is added to Li/NH3. Tentative mechanism is proposed. © 1987.

Full Text

Duke Authors

Cited Authors

  • Pradhan, SK; Thakker, KR; McPhail, AT

Published Date

  • January 1, 1987

Published In

Volume / Issue

  • 28 / 16

Start / End Page

  • 1813 - 1816

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/S0040-4039(00)95429-7

Citation Source

  • Scopus