Highly stereoselective radical addition to a trisubstituted alkene by low temperature photolysis of thiohydroxamic esters

Journal Article (Journal Article)

Low temperature carbon radical addition to α,β-unsaturated amides of trans-2,5-dimethylpyrrolidine was achieved in high yield with high diastereoselectivity by photolysis of Barton esters. Use of an olefin substituted with three electron withdrawing groups provides synthetic versatility and regiospecificity. © 1990.

Full Text

Duke Authors

Cited Authors

  • Scott, DM; McPhail, AT; Porter, NA

Published Date

  • January 1, 1990

Published In

Volume / Issue

  • 31 / 12

Start / End Page

  • 1679 - 1682

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/S0040-4039(00)88852-8

Citation Source

  • Scopus