Neocleordane diterpenoids and their artifacts from Teucrium olivarianum

Journal Article (Journal Article)

The aerial parts of Teucrium oliverianum yielded five new neocleordane diterpenoids (teucrolins A [4], B [5], C [6], D [7], and E [8]), three neocleordane diterpene artifacts (12-O-methylteucrolivin A [9], 12-O-methylteucrolin A [10], and 12-O-ethylteucrolin A [11]), and the three known diterpenoids teucrolivins A [1], B [2], and C [3]. In addition, four other known compounds were isolated: the sterol 24(S)-stigmasta-5,22,25-trien-3β-ol, the iridoid 8-O-acetylharpagide, and the flavones eupatorin and cirsiliol. The structural assignments of all new diterpenoids and their artifacts were based on 1D and 2D nmr spectral data, chemical derivatization, and X-ray crystallographic analysis of 10; the latter established the relative stereochemistry and the presence of the rare axial substitution at C-3 in 10 and related compounds. © 1993, American Chemical Society. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Al-Yahya, MA; Muhammad, I; Mirza, HH; El-Feraly, FS; McPhail, AT

Published Date

  • January 1, 1993

Published In

Volume / Issue

  • 56 / 6

Start / End Page

  • 830 - 842

Electronic International Standard Serial Number (EISSN)

  • 1520-6025

International Standard Serial Number (ISSN)

  • 0163-3864

Digital Object Identifier (DOI)

  • 10.1021/np50096a005

Citation Source

  • Scopus