Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis
The preparation and characterization of cyclic optically active (5R)- 3,4,5,6-tetrahydro-5-phenyl-2H-1,4-oxazin-2-one-N-oxide (2) is described. This nitrone, which is viewed as a template for the synthesis of γ- oxygenated α-amino acids, reacts with alkenes efficiently and with high stereospecificity.
Baldwin, SW; Young, BG; McPhail, AT
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