Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis

Journal Article (Journal Article)

The preparation and characterization of cyclic optically active (5R)- 3,4,5,6-tetrahydro-5-phenyl-2H-1,4-oxazin-2-one-N-oxide (2) is described. This nitrone, which is viewed as a template for the synthesis of γ- oxygenated α-amino acids, reacts with alkenes efficiently and with high stereospecificity.

Full Text

Duke Authors

Cited Authors

  • Baldwin, SW; Young, BG; McPhail, AT

Published Date

  • September 17, 1998

Published In

Volume / Issue

  • 39 / 38

Start / End Page

  • 6819 - 6822

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/S0040-4039(98)01474-9

Citation Source

  • Scopus