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Beta-lactams derived from the reaction of phenanthridines and 11H- dibenzo[b,e]azepin-11-one with phenyivaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461

Publication ,  Journal Article
Afonso, A; Rosenblum, SB; Puar, MS; McPhail, AT
Published in: Tetrahedron Letters
October 8, 1998

Phenanthridines 4 and the 11H-dibenzo[b,e]azepin-11-one 17 were used as the imine components in the ketene-imine β-lactam synthesis to provide the fused tetracyclic β-lactams 7, 8 and 18.

Duke Scholars

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

October 8, 1998

Volume

39

Issue

41

Start / End Page

7431 / 7434

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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ICMJE
MLA
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Afonso, A., Rosenblum, S. B., Puar, M. S., & McPhail, A. T. (1998). Beta-lactams derived from the reaction of phenanthridines and 11H- dibenzo[b,e]azepin-11-one with phenyivaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461. Tetrahedron Letters, 39(41), 7431–7434. https://doi.org/10.1016/S0040-4039(98)01648-7
Afonso, A., S. B. Rosenblum, M. S. Puar, and A. T. McPhail. “Beta-lactams derived from the reaction of phenanthridines and 11H- dibenzo[b,e]azepin-11-one with phenyivaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461.” Tetrahedron Letters 39, no. 41 (October 8, 1998): 7431–34. https://doi.org/10.1016/S0040-4039(98)01648-7.
Afonso, A., et al. “Beta-lactams derived from the reaction of phenanthridines and 11H- dibenzo[b,e]azepin-11-one with phenyivaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461.” Tetrahedron Letters, vol. 39, no. 41, Oct. 1998, pp. 7431–34. Scopus, doi:10.1016/S0040-4039(98)01648-7.
Journal cover image

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

October 8, 1998

Volume

39

Issue

41

Start / End Page

7431 / 7434

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry