Beta-lactams derived from the reaction of phenanthridines and 11H- dibenzo[b,e]azepin-11-one with phenyivaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461

Journal Article

Phenanthridines 4 and the 11H-dibenzo[b,e]azepin-11-one 17 were used as the imine components in the ketene-imine β-lactam synthesis to provide the fused tetracyclic β-lactams 7, 8 and 18.

Full Text

Duke Authors

Cited Authors

  • Afonso, A; Rosenblum, SB; Puar, MS; McPhail, AT

Published Date

  • October 8, 1998

Published In

Volume / Issue

  • 39 / 41

Start / End Page

  • 7431 - 7434

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/S0040-4039(98)01648-7

Citation Source

  • Scopus