New products from the reactions of artemisinin with ammonia and amines
Published
Journal Article
Reaction of artemisinin (1) with ammonia, methylamine, dimethylamine, and allylamine afforded five unexpected products 2-6, in addition to the previously reported compounds 7-12. The identities of the new compounds were established from their spectral data, by chemical derivatization and by comparison with published reports. The stereochemistries of compounds 5 and 6 were confirmed by single-crystal X-ray analysis.
Full Text
Duke Authors
Cited Authors
- Galal, AM; Ahmad, MS; El-Feraly, FS; McPhail, AT
Published Date
- January 1999
Published In
Volume / Issue
- 62 / 1
Start / End Page
- 54 - 58
PubMed ID
- 9917282
Pubmed Central ID
- 9917282
Electronic International Standard Serial Number (EISSN)
- 1520-6025
International Standard Serial Number (ISSN)
- 0163-3864
Digital Object Identifier (DOI)
- 10.1021/np980142v
Language
- eng