Application of ruthenium-induced macrocyclization for the construction of macrocyclic depsipeptides.

Journal Article

The synthesis of a biaryl ether containing macrocyclic depsipeptide 1 was achieved in 6% overall yield. The desired macrocycle was constructed by cyclization of a phenol into eta(6)-ruthenium complex. The ruthenium metal was subsequently photolytically deprotected to obtain the macrocycle 1.

Full Text

Duke Authors

Cited Authors

  • Venkatraman, S; Njoroge, FG; Girijavallabhan, V; McPhail, AT

Published Date

  • May 2002

Published In

Volume / Issue

  • 67 / 9

Start / End Page

  • 3152 - 3155

PubMed ID

  • 11975586

Pubmed Central ID

  • 11975586

Electronic International Standard Serial Number (EISSN)

  • 1520-6904

International Standard Serial Number (ISSN)

  • 0022-3263

Digital Object Identifier (DOI)

  • 10.1021/jo011106v

Language

  • eng