Application of ruthenium-induced macrocyclization for the construction of macrocyclic depsipeptides.

Journal Article (Journal Article)

The synthesis of a biaryl ether containing macrocyclic depsipeptide 1 was achieved in 6% overall yield. The desired macrocycle was constructed by cyclization of a phenol into eta(6)-ruthenium complex. The ruthenium metal was subsequently photolytically deprotected to obtain the macrocycle 1.

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Duke Authors

McPhail, Andrew T.

Cited Authors

Venkatraman, S; Njoroge, FG; Girijavallabhan, V; McPhail, AT

Published Date

May 2002

Published In

The Journal of Organic Chemistry

Volume / Issue

67 / 9

Start / End Page

3152 - 3155

PubMed ID

11975586

Electronic International Standard Serial Number (EISSN)

1520-6904

International Standard Serial Number (ISSN)

0022-3263

Digital Object Identifier (DOI)

10.1021/jo011106v

Language

eng