Asymmetric synthesis of 4,4-disubstituted-2-imidazoli-dinones: potent NK1 antagonists.

Published

Journal Article

[structure: see text] A highly efficient and practical synthesis of 4,4-Disubstituted-2-Imidazolidinones utilizing a "self-reproduction of the center of chirality" strategy is described.

Full Text

Duke Authors

Cited Authors

  • Reichard, GA; Stengone, C; Paliwal, S; Mergelsberg, I; Majmundar, S; Wang, C; Tiberi, R; McPhail, AT; Piwinski, JJ; Shih, N-Y

Published Date

  • November 2003

Published In

Volume / Issue

  • 5 / 23

Start / End Page

  • 4249 - 4251

PubMed ID

  • 14601972

Pubmed Central ID

  • 14601972

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol030104p

Language

  • eng