A nutritive control of independent ingestion in rat pups emerges by nine days of age.
Journal Article (Journal Article)
The emergence of controls of independent ingestion in rat pups was studied using nutritive (0.6 M glucose in saline or water) and vehicle gastric preloads. Two hours after preloading, ingestive responses were assessed in a 30-minute test of feeding from the floor. In 6-day-olds, all preloads had similar effects on consumption of a milk diet. In 9-day-olds, however, glucose-water preloads inhibited intake compared to water preloads. This inhibition was secondary to an effect on gastric emptying. Glucose preloads also inhibited intake in 12- and 15-day-olds. Behavioral observations indicated that feeding patterns were altered in response to glucose preloads in 9-day-olds. These results provide evidence for the emergence of a nutritive, postgastric control of independent ingestion between 6 and 9 days of age.
Full Text
Duke Authors
Cited Authors
- Swithers, SE; Hall, WG
Published Date
- November 1989
Published In
Volume / Issue
- 46 / 5
Start / End Page
- 873 - 879
PubMed ID
- 2516909
Electronic International Standard Serial Number (EISSN)
- 1873-507X
International Standard Serial Number (ISSN)
- 0031-9384
Digital Object Identifier (DOI)
- 10.1016/0031-9384(89)90051-6
Language
- eng