Developmental change in unilateral olfactory habituation is mediated by anterior commissure maturation.

Journal Article (Journal Article)

Habituation of an orienting response in rat pups was used to study the development of the anterior commissure (AC) and its role in olfactory memory. Six- and 12-day-old pups received odor presentations to one side of their olfactory system and were tested later for habituation to additional presentations made to either the trained or untrained side. Six-day-old pups remembered only on the trained side. Twelve-day-old pups remembered when tested on either side. Transection of the AC in 12-day-old pups before, but not after, training prevented the transfer of memory. Thus, between 6 and 12 days of age, olfactory cross-projections carried in the AC mature and provide a functional substrate for transfer, at the time of training, of a form of olfactory learning.

Full Text

Duke Authors

Cited Authors

  • King, C; Hall, WG

Published Date

  • October 1990

Published In

Volume / Issue

  • 104 / 5

Start / End Page

  • 796 - 807

PubMed ID

  • 2244986

Electronic International Standard Serial Number (EISSN)

  • 1939-0084

International Standard Serial Number (ISSN)

  • 0735-7044

Digital Object Identifier (DOI)

  • 10.1037//0735-7044.104.5.796


  • eng