Effects of hydrational state on ingestion in infant rats: is dehydration the only ingestive stimulus?

Published

Journal Article

The physiological stimulus for deprivation-enhanced ingestion was studied in developing rats. During an overnight deprivation period, continuous gastric infusions of isotonic saline or milk were made to 6- and 15-day-old rat pups in order to preferentially maintain hydrational or hydrational and nutritional status, respectively. Pups' ingestion was then studied in oral-infusion tests. In 6-day-old pups that received either milk or saline infusions, ingestion was depressed relative to intake in pups that were simply deprived. But in 15-day-old pups, only milk infusions reduced intake. These findings suggest that the increased ingestion stimulated by deprivation in pups less than a week of age results primarily from dehydration, and thus that nutrient-related feeding does not emerge until later in development.

Full Text

Duke Authors

Cited Authors

  • Phifer, CB; Ladd, MD; Hall, WG

Published Date

  • April 1991

Published In

Volume / Issue

  • 49 / 4

Start / End Page

  • 695 - 699

PubMed ID

  • 1881971

Pubmed Central ID

  • 1881971

Electronic International Standard Serial Number (EISSN)

  • 1873-507X

International Standard Serial Number (ISSN)

  • 0031-9384

Digital Object Identifier (DOI)

  • 10.1016/0031-9384(91)90304-7

Language

  • eng