Arginine vasopressin innoculates against age-related increases in sodium-dependent high affinity choline uptake and discrepancies in the content of temporal memory.

Published

Journal Article

Systemic injections of arginine vasopressin (AVP, 0.08 pressor units/kg i.p.) to mature rats (10-13 months) trained on a positively reinforced timing task prevented the age-related discrepancies in the content of temporal memory and the increases in sodium-dependent high affinity choline uptake (SDHCU) in the frontal cortex observed in control rats when the rats became aged (27-30 months). AVP administration had no effect on muscarinic receptor density as measured by [3H]quinuclidinyl benzilate (QNB) binding or on choline acetyltransferase (ChAT) levels in either the hippocampus or the frontal cortex.

Full Text

Duke Authors

Cited Authors

  • Meck, WH; Church, RM; Wenk, GL

Published Date

  • November 1986

Published In

Volume / Issue

  • 130 / 3

Start / End Page

  • 327 - 331

PubMed ID

  • 3792454

Pubmed Central ID

  • 3792454

Electronic International Standard Serial Number (EISSN)

  • 1879-0712

International Standard Serial Number (ISSN)

  • 0014-2999

Digital Object Identifier (DOI)

  • 10.1016/0014-2999(86)90287-6

Language

  • eng