Neuronal Ca2+ signalling takes the local route.


Journal Article (Review)

The past year has seen several sets of experimental results demonstrate that fast, large and highly localized rises in intracellular Ca2+ concentration can occur in neurons. These results confirm previous theoretical predictions of acute spatial compartmentalization of Ca2+ signalling, and document a form of signalling that may occur whenever rapid and local signal processing is the goal. The dimensions involved present severe challenges for attempts to directly measure these signalling events.

Full Text

Cited Authors

  • Augustine, GJ; Neher, E

Published Date

  • June 1992

Published In

Volume / Issue

  • 2 / 3

Start / End Page

  • 302 - 307

PubMed ID

  • 1643411

Pubmed Central ID

  • 1643411

Electronic International Standard Serial Number (EISSN)

  • 1873-6882

International Standard Serial Number (ISSN)

  • 0959-4388

Digital Object Identifier (DOI)

  • 10.1016/0959-4388(92)90119-6


  • eng