Instability of rRNA operons in Bacillus subtilis.


Journal Article

Many laboratory strains of Bacillus subtilis contain 9 rather than 10 rRNA operons due to deletions occurring within the rrnJ-rrnW or rrnI-rrnH-rrnG gene cluster. These operons are members of two sets of closely spaced clusters located in the cysA-aroI region. Analysis of rescued DNA from integrants with insertions into rrnG and rrnH indicated that these tandemly arranged operons allowed frequent deletions of an rrn operon equivalent. These events may arise spontaneously by intrachromosomal recombination or by simultaneous double crossovers with a multimeric integrative plasmid.

Full Text

Duke Authors

Cited Authors

  • Widom, RL; Jarvis, ED; LaFauci, G; Rudner, R

Published Date

  • February 1, 1988

Published In

Volume / Issue

  • 170 / 2

Start / End Page

  • 605 - 610

PubMed ID

  • 2828315

Pubmed Central ID

  • 2828315

International Standard Serial Number (ISSN)

  • 0021-9193

Digital Object Identifier (DOI)

  • 10.1128/jb.170.2.605-610.1988


  • eng

Conference Location

  • United States