Maturational trends of EEG-sleep measures in the healthy preterm neonate.


Journal Article

Five physiologic groupings of 45 EEG-sleep measures were acquired from serial 24-channel EEG-sleep recordings (i.e., sleep architecture, continuity, EEG spectral, phasic, and autonomic measures), utilizing 129 studies on 56 healthy preterm infants from 28 to 43 weeks postconceptional age (PCA) who were neurodevelopmentally normal on follow-up. Regression analyses chose the least number of measures that best reflected maturation. Four of 45 variables (i.e., spectral alpha energy during quiet sleep, total spectral EEG energy, arousal number during active sleep, and percentage of EEG discontinuity) most significantly explained brain maturation in neonates < 36 weeks PCA. Three of 45 variables (i.e., spectral theta and beta energies during active sleep and spectral alpha energy during quiet sleep) were most representative after 36 weeks PCA. Spectral EEG energies were the strongest indicators of maturation compared with other measures, particularly in near-term neonates.

Full Text

Duke Authors

Cited Authors

  • Scher, MS; Steppe, DA; Banks, DL; Guthrie, RD; Sclabassi, RJ

Published Date

  • May 1995

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 314 - 322

PubMed ID

  • 7546004

Pubmed Central ID

  • 7546004

Electronic International Standard Serial Number (EISSN)

  • 1873-5150

International Standard Serial Number (ISSN)

  • 0887-8994

Digital Object Identifier (DOI)

  • 10.1016/0887-8994(95)00052-h


  • eng