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Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana.

Publication ,  Journal Article
Heidel, AJ; Clarke, JD; Antonovics, J; Dong, X
Published in: Genetics
December 2004

This study investigated the fitness effects of four mutations (npr1, cpr1, cpr5, and cpr6) and two transgenic genotypes (NPR1-L and NPR1-H) affecting different points of the systemic acquired resistance (SAR) signaling pathway associated with pathogen defense in Arabidopsis thaliana. The npr1 mutation, which resulted in a failure to express SAR, had no effect on fitness under growth chamber conditions, but decreased fitness in the field. The expression of NPR1 positively correlated with the fitness in the field. Constitutive activation of SAR by cpr1, cpr5, and cpr6 generally decreased fitness in the field and under two nutrient levels in two growth chamber conditions. At low-nutrient levels, fitness differences between wild type and the constitutive mutants were unchanged or reduced (especially in cpr5). The reduced fitness of the constitutive mutants suggests that this pathway is costly, with the precise fitness consequences highly dependent on the environmental context.

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Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

December 2004

Volume

168

Issue

4

Start / End Page

2197 / 2206

Related Subject Headings

  • Seeds
  • RNA, Messenger
  • Plants, Genetically Modified
  • Mutation
  • Immunity, Innate
  • Developmental Biology
  • Arabidopsis Proteins
  • Arabidopsis
  • 3105 Genetics
  • 3101 Biochemistry and cell biology
 

Citation

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Heidel, A. J., Clarke, J. D., Antonovics, J., & Dong, X. (2004). Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana. Genetics, 168(4), 2197–2206. https://doi.org/10.1534/genetics.104.032193
Heidel, Andrew J., Joseph D. Clarke, Janis Antonovics, and Xinnian Dong. “Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana.Genetics 168, no. 4 (December 2004): 2197–2206. https://doi.org/10.1534/genetics.104.032193.
Heidel AJ, Clarke JD, Antonovics J, Dong X. Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana. Genetics. 2004 Dec;168(4):2197–206.
Heidel, Andrew J., et al. “Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana.Genetics, vol. 168, no. 4, Dec. 2004, pp. 2197–206. Epmc, doi:10.1534/genetics.104.032193.
Heidel AJ, Clarke JD, Antonovics J, Dong X. Fitness costs of mutations affecting the systemic acquired resistance pathway in Arabidopsis thaliana. Genetics. 2004 Dec;168(4):2197–2206.

Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

December 2004

Volume

168

Issue

4

Start / End Page

2197 / 2206

Related Subject Headings

  • Seeds
  • RNA, Messenger
  • Plants, Genetically Modified
  • Mutation
  • Immunity, Innate
  • Developmental Biology
  • Arabidopsis Proteins
  • Arabidopsis
  • 3105 Genetics
  • 3101 Biochemistry and cell biology