Validity of the Hamilton Endogenous Subscale: an independent replication.


Journal Article

We calculated scores on the Hamilton Endogenous Subscale (HES) (Thase et al., 1983) for 252 depressed inpatients. The HES scores were bimodally distributed, and HES classification was significantly associated with endogenous (Research Diagnostic Criteria) and melancholic (DSM-III) subtyping. Based on a cutoff score of 8, HES classification was not associated with either family history of specific psychiatric illness or abnormal dexamethasone suppression test (DST) results. When the cutoff was raised to 10, DST nonsuppression was more frequent in HES endogenous depressives, although we again failed to find an association with a family history of psychiatric disorders.

Full Text

Cited Authors

  • Zimmerman, M; Coryell, W; Pfohl, B; Stangl, D

Published Date

  • July 1, 1986

Published In

Volume / Issue

  • 18 / 3

Start / End Page

  • 209 - 215

PubMed ID

  • 3749383

Pubmed Central ID

  • 3749383

Electronic International Standard Serial Number (EISSN)

  • 1872-7123

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/0165-1781(86)90108-3


  • eng