An American validation study of the Newcastle diagnostic scale. I. Relationship with the dexamethasone suppression test.


Journal Article

The Newcastle diagnostic index was completed on 159 depressed in-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after controlling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.

Full Text

Cited Authors

  • Zimmerman, M; Pfohl, B; Stangl, D; Coryell, W

Published Date

  • November 1986

Published In

Volume / Issue

  • 149 /

Start / End Page

  • 627 - 630

PubMed ID

  • 3814955

Pubmed Central ID

  • 3814955

Electronic International Standard Serial Number (EISSN)

  • 1472-1465

International Standard Serial Number (ISSN)

  • 0007-1250

Digital Object Identifier (DOI)

  • 10.1192/bjp.149.5.627


  • eng