An American validation study of the Newcastle diagnostic scale. I. Relationship with the dexamethasone suppression test.
The Newcastle diagnostic index was completed on 159 depressed in-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after controlling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.
Zimmerman, M; Pfohl, B; Stangl, D; Coryell, W
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