New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement.
Publication
, Journal Article
Mao, Z; Baldwin, SW
Published in: Organic letters
July 2004
[reaction: see text] A new method for preparing spirocyclic oxindoles is presented. Featuring a [3,3]-sigmatropic enolate rearrangement, the three-step process converts carboxylic acid starting materials to oxidnole products in overall yields of 52-76%. The enolate rearrangement step occurs at -78 degrees C and provides easy access to oxindole products that have previously been difficult to prepare.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
July 2004
Volume
6
Issue
14
Start / End Page
2425 / 2428
Related Subject Headings
- Organic Chemistry
- 34 Chemical sciences
- 03 Chemical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Mao, Z., & Baldwin, S. W. (2004). New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement. Organic Letters, 6(14), 2425–2428. https://doi.org/10.1021/ol0491888
Mao, Zhan, and Steven W. Baldwin. “New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement.” Organic Letters 6, no. 14 (July 2004): 2425–28. https://doi.org/10.1021/ol0491888.
Mao Z, Baldwin SW. New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement. Organic letters. 2004 Jul;6(14):2425–8.
Mao, Zhan, and Steven W. Baldwin. “New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement.” Organic Letters, vol. 6, no. 14, July 2004, pp. 2425–28. Epmc, doi:10.1021/ol0491888.
Mao Z, Baldwin SW. New spirocyclic oxindole synthesis based on a hetero Claisen rearrangement. Organic letters. 2004 Jul;6(14):2425–2428.
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
July 2004
Volume
6
Issue
14
Start / End Page
2425 / 2428
Related Subject Headings
- Organic Chemistry
- 34 Chemical sciences
- 03 Chemical Sciences