Cystosarcoma phyllodes. Effective therapy with cisplatin and etoposide chemotherapy.


Journal Article

Cystosarcoma phyllodes is an unusual breast neoplasm that rarely metastasizes. Most series report chemotherapy, radiation, and hormonal therapy to be ineffective. Three patients were treated with cisplatin and etoposide combination chemotherapy with effective palliation in two patients. Radiation therapy was effective in controlling symptomatic metastasis in all three patients. Hormonal therapy was ineffective in two patients despite the presence of positive hormone receptors. Chemotherapy and radiotherapy may be more effective in the treatment of this tumor than has been reported, although there is no apparent role for hormonal therapy. Functional hormone receptors are probably not present.

Full Text

Duke Authors

Cited Authors

  • Burton, GV; Hart, LL; Leight, GS; Iglehart, JD; McCarty, KS; Cox, EB

Published Date

  • June 1, 1989

Published In

Volume / Issue

  • 63 / 11

Start / End Page

  • 2088 - 2092

PubMed ID

  • 2541882

Pubmed Central ID

  • 2541882

International Standard Serial Number (ISSN)

  • 0008-543X

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19890601)63:11<2088::aid-cncr2820631103>;2-c


  • eng

Conference Location

  • United States