Cellular and molecular analysis of plasmodium development in Physarum.


Journal Article

The development of an amoeba into a plasmodium involves extensive changes in cellular organisation and gene expression. The genetic basis of a number of recessive mutations that block plasmodium development has been elucidated. The stage at which development becomes abnormal has been determined for all the mutants, as has the terminal phenotype. In order to investigate the changes in gene expression that accompany plasmodium development, a cDNA library has been made using RNA isolated from cell populations in which development was occurring.

Full Text

Duke Authors

Cited Authors

  • Bailey, J; Solnica-Krezel, L; Lohman, K; Dee, J; Anderson, RW; Dove, WF

Published Date

  • November 1992

Published In

Volume / Issue

  • 16 / 11

Start / End Page

  • 1083 - 1090

PubMed ID

  • 1490279

Pubmed Central ID

  • 1490279

International Standard Serial Number (ISSN)

  • 0309-1651

Digital Object Identifier (DOI)

  • 10.1016/s0309-1651(05)80033-5


  • eng

Conference Location

  • England