Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose.

Published

Journal Article

A model synthesis of a nucleoside boranophosphoramidate prodrug with (L)-tryptophan methyl ester was accomplished in a one-pot reaction via an H-phosphonate approach. This new type of compound is expected to possess the potent antiviral and anticancer advantages conferred by boranophosphates and normal nucleoside amino acid phosphoramidate.

Full Text

Duke Authors

Cited Authors

  • Li, P; Shaw, BR

Published Date

  • January 2005

Published In

Volume / Issue

  • 24 / 5-7

Start / End Page

  • 675 - 678

PubMed ID

  • 16248012

Pubmed Central ID

  • 16248012

Electronic International Standard Serial Number (EISSN)

  • 1532-2335

International Standard Serial Number (ISSN)

  • 1525-7770

Digital Object Identifier (DOI)

  • 10.1081/ncn-200060244

Language

  • eng