Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.
Journal Article
A 4-kilobase DNA fragment carried by a recombinant lambda gt11 bacteriophage appears to contain most of the coding information for the 145-kDa subunit of the Saccharomyces cerevisiae mitochondrial RNA polymerase. The RPO41 gene is located on chromosome VI, as determined by hybridization to electrophoretically separated yeast chromosomes. Hybridization and gene disruption/replacement experiments show that the RPO41 gene exists in a single copy and that its product is required for transcription and maintenance of the mitochondrial genome.
Full Text
Duke Authors
Cited Authors
- Greenleaf, AL; Kelly, JL; Lehman, IR
Published Date
- May 1, 1986
Published In
Volume / Issue
- 83 / 10
Start / End Page
- 3391 - 3394
PubMed ID
- 3517858
Pubmed Central ID
- 3517858
Electronic International Standard Serial Number (EISSN)
- 1091-6490
International Standard Serial Number (ISSN)
- 0027-8424
Digital Object Identifier (DOI)
- 10.1073/pnas.83.10.3391
Language
- eng