Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.

Journal Article

A 4-kilobase DNA fragment carried by a recombinant lambda gt11 bacteriophage appears to contain most of the coding information for the 145-kDa subunit of the Saccharomyces cerevisiae mitochondrial RNA polymerase. The RPO41 gene is located on chromosome VI, as determined by hybridization to electrophoretically separated yeast chromosomes. Hybridization and gene disruption/replacement experiments show that the RPO41 gene exists in a single copy and that its product is required for transcription and maintenance of the mitochondrial genome.

Full Text

Duke Authors

Cited Authors

  • Greenleaf, AL; Kelly, JL; Lehman, IR

Published Date

  • May 1, 1986

Published In

Volume / Issue

  • 83 / 10

Start / End Page

  • 3391 - 3394

PubMed ID

  • 3517858

Pubmed Central ID

  • 3517858

Electronic International Standard Serial Number (EISSN)

  • 1091-6490

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.83.10.3391

Language

  • eng